(S)-MorfPhos

Name: (S)-MorfPhos
Brand: ChemScene
Availability: InStock
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CAS No. 185449-81-4
Cat. No. CS-0085218
Purity≥95%
MDL No.MFCD08276866

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HazMat Fee

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 185449-81-4

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Description

(S)-MorfPhos is a chiral phosphine ligand designed for asymmetric catalysis, featuring a rigid, electron-rich architecture that enhances enantioselectivity in transition metal-catalyzed reactions. This bench-stable, moisture-tolerant ligand integrates seamlessly into palladium- and nickel-mediated cross-coupling processes, delivering high stereocontrol under standard conditions.

Application

(S)-MorfPhos serves as a highly effective chiral ligand in palladium-catalyzed cross-coupling reactions, enabling efficient asymmetric synthesis of biaryl and alkenyl compounds. Its robust stereochemical integrity and broad functional group tolerance facilitate reliable enantioselective transformations under standard reaction conditions. The ligand exhibits excellent bench stability and simplifies purification in scalable processes, making it a practical choice for medicinal chemistry and process development workflows.

General Information

CAS No. 185449-81-4
Cat. No. CS-0085218
Purity ≥95%
MDL No. MFCD08276866
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₄H₂₀NO₃P
Molecular Weight 401.39
Synonym(s) 3,4-a']dinaphthalen-4-yl)Morpholine (S)-MorfPhos
SMILES C12=CC=CC=C1C=CC3=[C@]2[C@]4=C(C=CC=C5)C5=CC=C4OP(N6CCOCC6)O3

Computational Chemistry Data

TPSA 38.75
LogP 6.5646
H_Acceptors 4
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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(S)-MorfPhos

CAS No. 185449-81-4

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