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Structure of 840454-58-2
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This phosphine ligand features a rigid, electron-rich bicyclic scaffold with four sterically shielded aryl groups and a dimethylamino-substituted phosphorus center. Its design enhances stability, solubility in organic media, and performance in transition-metal catalysis under ambient conditions.
(1R,7R)-4-Dimethylamino-9,9-dimethyl-2,2,6,6-tetrakis(3,5-dimethylphenyl)-3,5,8,10-tetraoxa-4-phosphabicyclo[5.3.0]decane serves as a sterically encumbered, bench-stable phosphine reagent enabling efficient coupling reactions in complex molecule synthesis. Its electron-rich phosphorus center facilitates rapid oxidative addition and stable intermediates in palladium-catalyzed cross-couplings, while the bulky aryl groups confer enhanced resistance to oxidation and simplify purification. Functions effectively in Suzuki, Stille, and Negishi transformations with broad functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: