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Structure of 186593-26-0
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5-Nitro-3-pyridinol features a strategically positioned nitro group at the 5-position of the pyridinol scaffold, enhancing electron deficiency and enabling selective reactivity in transition metal-catalyzed couplings. This bench-stable heterocycle integrates readily into functionalized molecular architectures, serving as a key intermediate in the synthesis of bioactive compounds and advanced materials.
5-Nitro-3-pyridinol serves as a versatile building block for nitrogen-containing heterocycles, enabling efficient access to bioactive scaffolds through electrophilic substitution and metal-catalyzed coupling reactions. Its ortho-directing nitro group facilitates regioselective functionalization, while the phenolic hydroxyl supports derivatization and hydrogen bonding in medicinal chemistry applications. The compound exhibits bench stability and compatibility with standard purification protocols, making it well-suited for iterative synthesis in process and medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: