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Structure of 186593-43-1
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5-Amino-3-bromo-2-methylpyridine features a pyridine core functionalized with amino, bromo, and methyl groups at strategic positions, enabling selective coupling reactions. The electron-donating amino group enhances reactivity in cross-coupling processes, while the bromo substituent serves as a reliable handle for palladium-catalyzed transformations. This molecule combines synthetic versatility with robust stability under standard conditions.
5-Amino-3-bromo-2-methylpyridine serves as a versatile building block in medicinal chemistry and heterocyclic synthesis, enabling direct functionalization at multiple sites. The amino group facilitates nucleophilic substitution and coupling reactions, while the bromo substituent supports palladium-catalyzed cross-couplings such as Suzuki-Miyaura and Stille reactions. The methyl group enhances metabolic stability and influences regioselectivity in electrophilic substitutions. This compound exhibits excellent bench stability and compatibility with standard purification techniques, making it ideal for scalable synthesis of advanced pyridine-based scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: