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Structure of 1871-89-2
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Boc-Val-Ala-PAB-PNB is a cleavable peptide ADC linker. The Val-Ala will specifically be cleaved by Cathepsin B. Since this enzyme is only present in the lysosome, the ADC payload will be released only in the cell. PNP can be substituted by amine-bearing molecules.
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GHS Pictogram :
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GHS No : GHS07,GHS08,GHS09
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H372-H411
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Precautionary Statements : P260-P264-P270-P273-P330-P391-P501
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Lot numbers can be found on the outside label of a product: