(2-Amino-4-methoxyphenyl)methanol

Name: (2-Amino-4-methoxyphenyl)methanol
Brand: ChemScene
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CAS No. 187731-65-3
Cat. No. CS-0150495
Purity≥98%
MDL No.MFCD08275454

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(2-Amino-4-methoxyphenyl)methanol|CS-0150495

Structure of 187731-65-3

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Description

This bench-stable phenolic alcohol features a strategically positioned amino group and methoxy substituent, enabling direct incorporation into bioactive scaffolds. The ortho-aminomethoxy motif facilitates efficient coupling reactions under mild conditions, delivering functionalized intermediates for medicinal chemistry applications.

Application

(2-Amino-4-methoxyphenyl)methanol serves as a versatile building block for pharmaceutical and agrochemical synthesis, enabling efficient access to substituted aniline derivatives. Its ortho-amino and methoxy functionalities offer directed metallation and selective functionalization potential. The benzylic alcohol group facilitates downstream transformations such as oxidation, etherification, or coupling reactions. Exhibiting good bench stability and compatibility with standard protecting group strategies, it functions reliably in multi-step synthetic sequences.

General Information

CAS No. 187731-65-3
Cat. No. CS-0150495
Purity ≥98%
MDL No. MFCD08275454
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₁NO₂
Molecular Weight 153.18
Synonym(s) Benzenemethanol, 2-amino-4-methoxy- (9CI)
SMILES COC1=CC(=C(C=C1)CO)N

Computational Chemistry Data

TPSA 55.48
LogP 0.7697
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 2

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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(2-Amino-4-methoxyphenyl)methanol

CAS No. 187731-65-3

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