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Ethyl 7-aminofuro[2,3-b]pyrazine-6-carboxylate

  • CAS No. 187732-95-2

  • Cat. No. CS-0089835
  • Purity≥97%
  • MDL No.MFCD09909670

*For research and further manufacturing use only, not for direct human use.

Ethyl 7-aminofuro[2,3-b]pyrazine-6-carboxylate|CS-0089835

Structure of 187732-95-2

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General Information

  • CAS No. 187732-95-2
  • Cat. No. CS-0089835
  • Purity ≥97%
  • MDL No. MFCD09909670
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉N₃O₃
  • Molecular Weight 207.19
  • Synonym(s) Furo[2,3-b]pyrazine-6-carboxylic acid, 7-amino-, ethyl ester (9CI) USP/EP/BP
  • SMILES O=C(C1=C(N)C2=NC=CN=C2O1)OCC

Description

Ethyl 7-aminofuro[2,3-b]pyrazine-6-carboxylate features a fused heterocyclic core with a pendant amino group enabling direct functionalization. This electron-rich scaffold integrates readily into complex molecular architectures, offering high stability under standard conditions and compatibility with diverse coupling reactions.

Application

Ethyl 7-aminofuro[2,3-b]pyrazine-6-carboxylate serves as a versatile building block for the synthesis of furo[2,3-b]pyrazine-based heterocycles. The amino and ester functionalities enable sequential functionalization via coupling, amidation, and cyclization reactions. Its bench-stable nature and compatibility with standard reaction conditions facilitate efficient access to advanced intermediates for medicinal chemistry and API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   91.24
  • LogP   0.9817
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   2

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