tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate

Name: tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate
Brand: ChemScene
Availability: OutOfStock
Rating: 5 (1 reviews)

CAS No. 190141-99-2
Cat. No. CS-0036146
Molecule weight202.25
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate|CS-0036146

Structure of 190141-99-2

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 190141-99-2
Cat. No. CS-0036146
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₈N₂O₃
Molecular Weight 202.25
Synonym(s) tert-Butyl 3-amino-4-hydroxy-1-pyrrolidinecarboxylate
SMILES CC(C)(C)OC(=O)N1CC(C(C1)O)N

Description

tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate features a pyrrolidine core with strategically positioned amino and hydroxyl groups, enabling direct incorporation into complex heterocyclic scaffolds. The tert-butyl ester group provides bench-stable protection for the amine, simplifying purification and handling during synthesis. This bifunctional building block supports efficient access to bioactive nitrogen-containing compounds in medicinal chemistry workflows.

Application

tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate serves as a versatile building block in medicinal chemistry, enabling the synthesis of complex pyrrolidine-containing scaffolds. The protected amine and hydroxyl groups offer orthogonal reactivity for sequential functionalization, while the tert-butyl carbamate provides stability and ease of removal under mild acidic conditions. Its compatibility with standard coupling and reduction protocols facilitates efficient access to diverse heterocyclic architectures relevant to API development.

Synthesis

Route1
- In-stock
  
  114214-49-2
- ~96%
- In-stock
  
  190141-99-2
References
- WO2010/114971 A1, ; Page/Page column 153 ;
Route2
- 203434-45-1
- ~88%
- In-stock
  
  190141-99-2
References
- Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 3 p. 221 - 226
Route3
- In-stock
  
  73286-70-1
- ~%
- In-stock
  
  190141-99-2
References
- Bioorganic and Medicinal Chemistry Letters, , vol. 8, # 3 p. 221 - 226

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 75.79
LogP -0.0747
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Aliphatic heterocycle compounds Pyrrolidine compounds

Key Words

190141-99-2 sigma190141-99-2 manufacturer190141-99-2 price190141-99-2 structure190141-99-2 SDSbuy 190141-99-2190141-99-2 supplier190141-99-2 uses190141-99-2 molecular weightprice of 190141-99-2190141-99-2 chemical name formula of 190141-99-2

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl 3-amino-4-hydroxypyrrolidine-1-carboxylate

CAS No. 190141-99-2

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words