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Structure of 190656-34-9
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(5-Bromo-2-fluorophenyl)methanamine features a strategically positioned bromo and fluoro substituent on the aromatic ring, delivering enhanced electronic modulation and metabolic stability. This bench-stable amine integrates readily into pharmaceutical scaffolds via coupling reactions, offering precise functionalization in late-stage synthesis.
(5-Bromo-2-fluorophenyl)methanamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated arylamines through standard coupling reactions. Its orthogonal reactivity profile—combining bromide for Pd-catalyzed cross-couplings and fluoride for directed functionalization—facilitates efficient access to complex heterocycles and API intermediates. The compound exhibits good bench stability and is readily purified by distillation or crystallization, supporting scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: