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Structure of 191014-55-8
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4-Fluoro-2-methoxybenzonitrile features a strategically positioned nitrile group flanked by fluorine and methoxy substituents, enabling selective coupling reactions in medicinal chemistry. This electron-deficient aromatic core integrates readily into bioactive scaffolds under standard conditions, offering enhanced metabolic stability and tunable solubility for drug discovery applications.
4-Fluoro-2-methoxybenzonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to substituted benzimidazoles and other heterocyclic scaffolds via nucleophilic aromatic substitution. The ortho-methoxy group enhances reactivity toward amines and thiols, while the fluorine acts as a reliable leaving group under mild conditions. Bench-stable and compatible with common purification methods, it facilitates streamlined synthesis of bioactive intermediates.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H302+H312-H315-H319-H331-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: