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Structure of 192508-36-4
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This fluorinated arylacetic acid features a para-nitro group enhancing electrophilicity for cross-coupling reactions. The 4-fluoro substituent enables selective functionalization via palladium catalysis. Bench-stable and moisture-tolerant, it integrates readily into pharmaceutical intermediates requiring electron-deficient aromatic motifs.
2-(4-Fluoro-3-nitrophenyl)acetic acid serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-fluoro and meta-nitro substituents enable directed functionalization, while the carboxylic acid group facilitates straightforward derivatization via amide, ester, or acyl chloride formation. The compound exhibits good bench stability and is compatible with standard coupling reactions, making it well-suited for medicinal chemistry campaigns requiring nitro-aryl motifs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: