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Structure of 403-15-6
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4-Fluoro-3-methylbenzoic acid features a strategically positioned fluorine atom and methyl group on the aromatic ring, enhancing electronic effects and metabolic stability. This combination improves binding affinity in target-directed synthesis and supports efficient derivatization under standard conditions.
4-Fluoro-3-methylbenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-substituted aryl motif provides enhanced metabolic stability and modulates electronic properties, while the carboxylic acid group facilitates direct coupling reactions. The compound exhibits excellent bench stability and compatibility with standard functional group transformations, making it well-suited for scalable synthesis and downstream derivatization.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: