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Structure of 19346-47-5
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2-Fluoro-4-methyl-5-nitropyridine is a bench-stable, electron-deficient heterocycle featuring a fluorine atom at the 2-position and a nitro group at the 5-position. This combination enhances electrophilicity at the pyridine ring, enabling efficient coupling reactions in cross-coupling and nucleophilic substitution processes. The methyl substituent provides steric and electronic modulation, improving solubility and reactivity control in synthetic transformations.
2-Fluoro-4-methyl-5-nitropyridine serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The fluorine and nitro groups provide orthogonal reactivity for selective transformations, while the methyl group enhances metabolic stability. Its bench-stable nature and compatibility with diverse reaction conditions facilitate rapid access to substituted pyridine scaffolds relevant to API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: