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CS-W001157 4
Total: USD 88.00

Phenyl methylcarbamate

  • CAS No. 1943-79-9

  • Cat. No. CS-0160301
  • Molecule weight151.16
  • Purity≥97%
  • MDL No.MFCD01738783

*For research and further manufacturing use only, not for direct human use.

Phenyl methylcarbamate|CS-0160301

Structure of 1943-79-9

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General Information

  • CAS No. 1943-79-9
  • Cat. No. CS-0160301
  • Purity ≥97%
  • MDL No. MFCD01738783
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉NO₂
  • Molecular Weight 151.16
  • Synonym(s) PHENYL-N-METHYL-CARBAMATE
  • SMILES O=C(OC1=CC=CC=C1)NC

Description

Phenyl methylcarbamate delivers a stable, bench-ready carbamate functionality for synthetic applications. This compound integrates a phenyl-anchored carbamate group that enables efficient coupling in amide bond formation and peptide synthesis. Its moisture-tolerant character simplifies handling under standard laboratory conditions, while the aromatic core enhances solubility in organic media.

Application

Phenyl methylcarbamate serves as a stable, bench-friendly carbamate protecting group for amines, enabling selective N-alkylation and orthogonal deprotection under mild conditions. It facilitates efficient peptide coupling protocols and functions as a key intermediate in the synthesis of heterocyclic scaffolds and bioactive molecules. Its predictable reactivity and compatibility with diverse functional groups make it a practical choice in multi-step organic syntheses.

Synthesis

  • Route1
    • null|null
      1885-14-9
    • null|null
      74-89-5
    • ~88%
    • In-stock
      Phenyl methylcarbamate|CS-0160301
      1943-79-9

    References

    • Takeda Pharmaceutical Company Limited Patent: EP1500658 A1, 2005 ; Location in patent: Page 51-52 ; EP 1500658 A1
  • Route2
    • null|null
      593-51-1
    • null|null
      1885-14-9
    • ~61%
    • In-stock
      Phenyl methylcarbamate|CS-0160301
      1943-79-9

    References

    • Eisai Co., Ltd. Patent: EP1522540 A1, 2005 ; Location in patent: Page/Page column 48 ; EP 1522540 A1
  • Route3
    • null|null
      624-83-9
    • null|null
      108-95-2
    • ~79%
    • In-stock
      Phenyl methylcarbamate|CS-0160301
      1943-79-9

    References

    • Ivanov; Smirnova Pharmaceutical Chemistry Journal, 1997 , vol. 31, # 1 p. 12 - 14

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.33
  • LogP   1.4048
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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