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CS-W001157 4
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Bicyclo[4.2.0]octa-1,3,5-trien-3-ylboronic acid

  • CAS No. 195730-31-5

  • Cat. No. CS-0043999
  • Purity≥97%
  • MDL No.MFCD09752664
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Bicyclo[4.2.0]octa-1,3,5-trien-3-ylboronic acid|CS-0043999

Structure of 195730-31-5

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Description

Bicyclo[4.2.0]octa-1,3,5-trien-3-ylboronic acid delivers a rigid, electron-deficient boronate moiety tethered to a strained bicyclic framework. This structure enables selective cross-coupling reactions under mild conditions, leveraging its inherent stability and predictable reactivity in synthetic sequences.

Application

Bicyclo[4.2.0]octa-1,3,5-trien-3-ylboronic acid serves as a versatile building block for transition-metal-catalyzed couplings, enabling efficient construction of complex polycyclic architectures. Its stable boronic acid functionality facilitates Suzuki-Miyaura reactions with broad functional group tolerance, offering reliable access to substituted terpene-derived scaffolds and fused-ring systems commonly encountered in natural product synthesis and medicinal chemistry applications.

General Information

  • CAS No. 195730-31-5
  • Cat. No. CS-0043999
  • Purity ≥97%
  • MDL No. MFCD09752664
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BO₂
  • Molecular Weight 147.97
  • Synonym(s) cyclobutabenzen-4-ylboronic acid
  • SMILES OB(C1=CC=C2CCC2=C1)O

Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.535
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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