2-[(4R)-4,5-Dihydro-4-phenyl-2-oxazolyl]-6-methylpyridine

Name: 2-[(4R)-4,5-Dihydro-4-phenyl-2-oxazolyl]-6-methylpyridine
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CAS No. 199277-73-1
Cat. No. CS-0120406
Purity≥95%
MDL No.None

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FedEx Limited Quantities Ground	$0.00
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2-[(4R)-4,5-Dihydro-4-phenyl-2-oxazolyl]-6-methylpyridine|CS-0120406

Structure of 199277-73-1

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Description

This pyridine derivative features a chiral oxazoline moiety that imparts enhanced stereocontrol in asymmetric synthesis. The phenyl-substituted oxazoline ring combines with the electron-deficient pyridine core to enable efficient coupling reactions under mild conditions. Designed for use in catalytic systems requiring precise spatial orientation, this compound delivers high reactivity and stability during functional group manipulations.

Application

2-[(4R)-4,5-Dihydro-4-phenyl-2-oxazolyl]-6-methylpyridine serves as a versatile heterocyclic building block in medicinal chemistry, enabling the construction of complex scaffolds via standard coupling and functionalization reactions. Its bench-stable oxazoline core exhibits excellent functional group tolerance and compatibility with palladium-catalyzed transformations, facilitating efficient access to bioactive molecules.

General Information

CAS No. 199277-73-1
Cat. No. CS-0120406
Purity ≥95%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₅H₁₄N₂O
Molecular Weight 238.29
Synonym(s) (R)-2-(6-Methylpyridin-2-yl)-4-phenyl-4,5-dihydrooxazole
SMILES CC1=CC=CC(C2=N[C@H](C3=CC=CC=C3)CO2)=N1

Computational Chemistry Data

TPSA 34.48
LogP 2.90812
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 2

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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2-[(4R)-4,5-Dihydro-4-phenyl-2-oxazolyl]-6-methylpyridine

CAS No. 199277-73-1

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