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Structure of 200064-11-5
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4-(5-Bromopyridin-2-yl)morpholine features a brominated pyridine ring fused to a morpholine heterocycle, delivering a robust platform for transition-metal-catalyzed coupling reactions. The electron-deficient pyridine moiety enhances reactivity in cross-coupling processes, while the morpholine nitrogen provides solubility and handles well under standard conditions. This scaffold integrates efficiently into diverse molecular architectures.
4-(5-Bromopyridin-2-yl)morpholine serves as a versatile building block in medicinal chemistry, enabling efficient Suzuki and Buchwald–Hartwig coupling reactions. The bromopyridine moiety provides a reliable handle for cross-coupling, while the morpholine ring offers moderate basicity and hydrogen-bonding capacity, enhancing solubility and modulating pharmacokinetic properties. Its bench stability and compatibility with standard reaction conditions make it a practical choice for constructing complex heterocyclic scaffolds in API development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: