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Structure of 203854-49-3
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Fmoc-β-HoGlu(OtBu)-OH is a protected amino acid derivative featuring a β-hydroxyglutamic acid scaffold with orthogonal side-chain protection. This variant enables selective conjugation in peptide synthesis, where the hydroxyl group remains available for downstream modifications. The Fmoc group ensures efficient stepwise coupling under standard conditions, while the OtBu ester provides stability during purification and handling.
Fmoc-β-HoGlu(OtBu)-OH serves as a key building block for the synthesis of peptide conjugates and cyclic peptides, leveraging the orthogonal reactivity of its Fmoc group and stable OtBu ester. Its β-hydroxyglutamic acid scaffold enables precise incorporation of hydroxyl functionality into peptide backbones, facilitating downstream derivatization or structural modulation. The compound exhibits excellent bench stability, simplifies purification via standard chromatographic methods, and is compatible with established solid-phase peptide synthesis protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: