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Structure of 206181-90-0
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3-Chloropyridine-2-carboxaldehyde delivers a reactive aldehyde group positioned ortho to a chlorine-substituted pyridine ring, enabling direct coupling in heterocyclic synthesis. This electron-deficient scaffold facilitates efficient imine formation and transition metal-catalyzed cross-couplings under standard conditions.
3-Chloropyridine-2-carboxaldehyde serves as a versatile building block in medicinal chemistry, enabling direct incorporation of both chloropyridine and aldehyde functionalities into target molecules. Its aldehyde group facilitates nucleophilic addition, reductive amination, and condensation reactions, while the ortho-chloro substituent offers site-specific derivatization potential via palladium-catalyzed cross-coupling. The compound exhibits good bench stability and is compatible with standard purification protocols, making it a practical choice for constructing heterocyclic scaffolds and bioactive intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: