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Structure of 207115-22-8
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4-Bromo-2-iodophenol features a phenolic hydroxyl group flanked by bromo and iodo substituents at the 4- and 2-positions, respectively. This ortho-halogenated scaffold enables selective cross-coupling reactions in palladium-catalyzed transformations. The molecule exhibits enhanced reactivity due to the electron-withdrawing nature of the halogens, facilitating efficient C–C bond formation under mild conditions.
4-Bromo-2-iodophenol serves as a versatile diaryl building block for palladium-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds. The ortho-iodo group facilitates selective coupling with boronic acids, esters, and stannanes, while the para-bromo substituent offers complementary reactivity. Bench-stable and readily purified by recrystallization, it functions reliably in iterative synthesis workflows requiring functional group tolerance and predictable regiochemistry.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: