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Structure of 858855-11-5
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5-Bromo-2-iodophenol features a phenolic hydroxyl group flanked by bromo and iodo substituents at the 5- and 2-positions, respectively. This electron-deficient aromatic scaffold enables direct coupling in transition-metal-catalyzed reactions. The molecule exhibits enhanced stability under standard bench conditions and serves as a key building block for bioactive heterocycles and functionalized aryl systems.
5-Bromo-2-iodophenol serves as a versatile building block in the synthesis of functionalized aryl scaffolds, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromo and iodo substituents facilitate sequential transformations, while the phenolic hydroxyl group offers site-specific derivatization and enhanced solubility. Bench-stable and readily purified by recrystallization, it functions efficiently in standard coupling protocols and heterocycle construction workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: