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CS-W001157 4
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6-(Dimethylamino)picolinaldehyde

  • CAS No. 208110-83-2

  • Cat. No. CS-0620159
  • Molecule weight150.18
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-(Dimethylamino)picolinaldehyde|CS-0620159

Structure of 208110-83-2

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General Information

  • CAS No. 208110-83-2
  • Cat. No. CS-0620159
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O
  • Molecular Weight 150.18
  • Synonym(s) None
  • SMILES O=CC1=NC(N(C)C)=CC=C1

Description

6-(Dimethylamino)picolinaldehyde features a pyridine ring bearing an electron-rich dimethylamino group and a reactive aldehyde at adjacent positions. This combination enables efficient coupling in condensation reactions, particularly in the synthesis of heterocyclic scaffolds and fluorescent probes. The molecule exhibits enhanced solubility in polar solvents and maintains stability under standard bench conditions.

Application

6-(Dimethylamino)picolinaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to heterocyclic scaffolds via condensation and cyclization reactions. Its aldehyde functionality exhibits high reactivity with amines and hydrazines, while the dimethylamino group enhances electron density at the pyridine ring, facilitating electrophilic substitutions. The compound demonstrates excellent bench stability and ease of purification, making it well-suited for iterative synthesis campaigns and API intermediate development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   33.2
  • LogP   0.9601
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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