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Structure of 209920-43-4
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6-Methyl-1H-indole-3-carboxylic acid features a sterically hindered indole core with a carboxylic acid group at the 3-position, enabling direct conjugation in peptide and heterocyclic syntheses. The methyl substituent enhances metabolic stability and modulates electronic properties for use in medicinal chemistry scaffolds.
6-Methyl-1H-indole-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling efficient access to indole-based scaffolds through standard amide coupling and decarboxylation protocols. Its carboxylic acid functionality exhibits excellent compatibility with diverse coupling reagents, while the methyl group enhances metabolic stability and modulates electronic properties. Bench-stable and readily purified by recrystallization, it functions reliably in multistep syntheses targeting bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: