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Structure of 210169-05-4
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5-Fluoropyridin-3-amine features a fluorine atom at the 5-position and an amino group at the 3-position of a pyridine ring, delivering a potent electron-deficient heteroaromatic scaffold. This configuration enables direct incorporation into pharmaceutical intermediates, facilitating coupling reactions and enabling access to bioactive molecules through transition-metal-catalyzed transformations.
5-Fluoropyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling direct incorporation into diverse heterocyclic scaffolds. Its reactivity is well-documented in cross-coupling and nucleophilic substitution reactions, particularly with aryl halides and sulfonyl chlorides. The molecule exhibits excellent bench stability and facilitates efficient purification, making it ideal for multi-step synthesis workflows targeting kinase inhibitors and other bioactive compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P302+P352
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Lot numbers can be found on the outside label of a product: