3-Amino-4-chloropyridine

Name: 3-Amino-4-chloropyridine
Brand: ChemScene
Availability: InStock
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CAS No. 20511-15-3
Cat. No. CS-D1565
Purity≥98%
MDL No.MFCD00235124

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 20511-15-3

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Description

3-Amino-4-chloropyridine is a heterocyclic building block featuring an electron-rich pyridine core with complementary amino and chloro substituents. This combination enables selective functionalization in late-stage derivatization, particularly in pharmaceutical and agrochemical synthesis. The molecule exhibits favorable solubility and stability under standard conditions, facilitating straightforward incorporation into complex molecular architectures.

Application

3-Amino-4-chloropyridine serves as a versatile building block in medicinal chemistry, enabling direct incorporation into heterocyclic scaffolds via cross-coupling and nucleophilic substitution reactions. The amino group facilitates derivatization, while the chloro substituent provides a reliable handle for palladium-catalyzed transformations. Its stability under standard reaction conditions and compatibility with diverse functional groups make it a practical choice for synthesizing API intermediates and kinase inhibitor frameworks.

General Information

CAS No. 20511-15-3
Cat. No. CS-D1565
Purity ≥98%
MDL No. MFCD00235124
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₅ClN₂
Molecular Weight 128.56
Synonym(s) None
SMILES NC1=C(Cl)C=CN=C1

Computational Chemistry Data

TPSA 38.91
LogP 1.3172
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Amine

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

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3-Amino-4-chloropyridine

CAS No. 20511-15-3

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