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Structure of 210240-20-3
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4-Aminotetrahydro-2H-thiopyran 1,1-dioxide features a saturated thiopyran ring with dual sulfone functionalities, delivering enhanced polarity and metabolic stability. The primary amine enables direct derivatization, while the electron-withdrawing sulfones modulate reactivity. This scaffold serves as a robust building block for bioactive molecule synthesis, particularly in medicinal chemistry where solubility and stability are critical.
4-Aminotetrahydro-2H-thiopyran 1,1-dioxide serves as a versatile sulfonamide-containing scaffold in medicinal chemistry, offering a rigid, polar heterocyclic core with excellent functional group tolerance. The amine functionality enables facile derivatization via amidation, alkylation, or acylation, while the sulfonyl group enhances solubility and metabolic stability. Its bench-stable nature and compatibility with standard coupling protocols make it ideal for building diverse compound libraries in target-oriented synthesis.
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GHS Pictogram :
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GHS No : GHS05,GHS07,GHS09
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H315-H318-H335-H411
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P501
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Lot numbers can be found on the outside label of a product: