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CS-W001157 4
Total: USD 88.00

Methyl (2R,4S)-4-hydroxypiperidine-2-carboxylate

  • CAS No. 211058-81-0

  • Cat. No. CS-0473325
  • Molecule weight159.18
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl (2R,4S)-4-hydroxypiperidine-2-carboxylate|CS-0473325

Structure of 211058-81-0

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General Information

  • CAS No. 211058-81-0
  • Cat. No. CS-0473325
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃NO₃
  • Molecular Weight 159.18
  • Synonym(s) 2-Piperidinecarboxylicacid,4-hydroxy-,methylester,(2R,4S)-(9CI)
  • SMILES COC(=O)[C@H]1C[C@@H](O)CCN1

Synthesis

  • Route1
    • Methyl (2R,4S)-4-hydroxy-1-((R)-1-phenylethyl)piperidine-2-carboxylate|CS-0512589
      177944-17-1
    • ~82%
    • Methyl (2R,4S)-4-hydroxypiperidine-2-carboxylate|CS-0473325
      211058-81-0

    References

    • Molnar, Tuende; Visy, Julia; Simon, Agnes; Moldvai, Istvan; Temesvari-Major, Eszter; Doernyei, Gabor; Fekete, Erzsebet Kutine; Kardos, Julianna Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 23 p. 6290 - 6292
  • Route2
    • null|null
      911051-21-3
    • ~%
    • Methyl (2R,4S)-4-hydroxypiperidine-2-carboxylate|CS-0473325
      211058-81-0

    References

    • Cordero, Franca M.; Bonollo, Simona; Machetti, Fabrizio; Brandi, Alberto European Journal of Organic Chemistry, 2006 , # 14 p. 3235 - 3241
  • Route3
    • null|null
      67-56-1
    • null|null
      5162-44-7
    • Glyoxalic acid 50%w/w in water|CS-W019807
      298-12-4
    • ~%
    • Methyl (2R,4S)-4-hydroxypiperidine-2-carboxylate|CS-0473325
      211058-81-0
    • Methyl (2S,4R)-4-hydroxypiperidine-2-carboxylate|CS-0470632
      211058-80-9

    References

    • Sata, Noriko U; Kuwahara, Ryuji; Murata, Yuko Tetrahedron Letters, 2002 , vol. 43, # 1 p. 115 - 118

Safety Information

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GHS Pictogram : N/A
GHS No : N/A
Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   -0.7277
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

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