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Structure of 1174020-40-6
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This tert-butyl (3S,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate features a stereochemically defined piperidine scaffold with fluorine and hydroxyl groups positioned for precise molecular integration. The bench-stable tert-butyl carbamate protects the amine during synthetic manipulations, enabling efficient incorporation into bioactive molecules. This configuration supports conformational rigidity in target compounds, enhancing binding affinity and metabolic stability.
tert-Butyl (3S,4R)-3-fluoro-4-hydroxypiperidine-1-carboxylate serves as a stereochemically defined building block for fluorinated piperidine scaffolds. The protected hydroxyl group enables selective functionalization, while the fluorine substituent imparts metabolic stability and modulates electronic properties. This intermediate exhibits excellent bench stability and facilitates downstream transformations including coupling reactions and cyclizations, making it valuable in medicinal chemistry and API synthesis.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: