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Structure of 21512-16-3
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5-Formylthiophene-2-carbonitrile features a conjugated thiophene core bearing an electron-deficient formyl group and a nitrile functionality, enabling efficient coupling in cross-coupling and multicomponent reactions. This bifunctional scaffold integrates readily into heterocyclic architectures under mild conditions, offering high stability and compatibility with diverse reaction media.
5-Formylthiophene-2-carbonitrile serves as a versatile bifunctional building block for heterocyclic synthesis, enabling efficient access to substituted thiophene scaffolds. The aldehyde and nitrile groups provide orthogonal reactivity for sequential transformations—such as nucleophilic additions, condensations, and cyclizations—facilitating the construction of complex pharmacophores. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for medicinal chemistry campaigns and process-scale applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P264-P270-P280
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Lot numbers can be found on the outside label of a product: