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tert-Butyltrimethylsilane-PEG2-NH2

  • CAS No. 215297-17-9

  • Cat. No. CS-0528770
  • Purity≥98%
  • MDL No.MFCD24386371

*For research and further manufacturing use only, not for direct human use.

tert-Butyltrimethylsilane-PEG2-NH2|CS-0528770

Structure of 215297-17-9

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General Information

  • CAS No. 215297-17-9
  • Cat. No. CS-0528770
  • Purity ≥98%
  • MDL No. MFCD24386371
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₅NO₂Si
  • Molecular Weight 219.40
  • Synonym(s) None
  • SMILES O(CCO[Si](C)(C)C(C)(C)C)CCN

Description

This silyl-protected diamine features a bifunctional ether-amino backbone, enabling selective derivatization in synthetic workflows. The tert-butyldimethylsilyl group provides robust protection against nucleophilic attack and moisture, while the terminal amine remains accessible for coupling reactions under standard conditions.

Application

2-(2-((tert-Butyldimethylsilyl)oxy)ethoxy)ethanamine serves as a versatile silyl-protected ether amine building block, enabling selective deprotection in late-stage synthesis. Its tert-butyldimethylsilyl (TBS) group offers excellent bench stability and orthogonal compatibility with common functional groups. The molecule facilitates efficient conjugation, glycosylation, and peptide coupling workflows, while the aliphatic amine moiety supports diverse derivatization—ideal for medicinal chemistry campaigns requiring robust protection strategies.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   1.9835
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   6

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