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CS-W001157 4
Total: USD 88.00

Pyridazine-3-carboxylic acid

  • CAS No. 2164-61-6

  • Cat. No. CS-W004823
  • Purity≥97%
  • MDL No.MFCD01646333
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Pyridazine-3-carboxylic acid|CS-W004823

Structure of 2164-61-6

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Description

Pyridazine-3-carboxylic acid features a rigid, electron-deficient heterocyclic core paired with a carboxylic acid group, enabling direct incorporation into bioactive scaffolds. This structure supports hydrogen bonding and metal coordination, enhancing binding affinity in medicinal chemistry applications. The compound exhibits bench-stable handling characteristics and compatibility with standard peptide coupling protocols.

Application

Pyridazine-3-carboxylic acid serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through standard amide coupling and cyclization protocols. Its carboxylic acid functionality facilitates direct derivatization or activation for peptide-like linkages, while the electron-deficient pyridazine core supports nucleophilic substitution and transition-metal-catalyzed cross-coupling reactions. The compound exhibits good bench stability and is readily purified by recrystallization, making it suitable for scalable synthesis and API intermediate development.

General Information

  • CAS No. 2164-61-6
  • Cat. No. CS-W004823
  • Purity ≥97%
  • MDL No. MFCD01646333
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄N₂O₂
  • Molecular Weight 124.10
  • Synonym(s) 3-pyridazinylcarboxylic acid
  • SMILES C1=C(N=NC=C1)C(O)=O

Computational Chemistry Data

  • TPSA   63.08
  • LogP   0.1748
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352

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