2-Amino-5-fluoropyridine

Name: 2-Amino-5-fluoropyridine
Brand: ChemScene
Availability: InStock
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CAS No. 21717-96-4
Cat. No. CS-B0957
Purity≥98%
MDL No.MFCD01861120

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 21717-96-4

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Description

2-Amino-5-fluoropyridine features a strategically positioned fluorine atom and amino group on the pyridine ring, enabling efficient incorporation into bioactive molecules. This electron-deficient heterocycle serves as a key scaffold in medicinal chemistry, offering enhanced metabolic stability and tunable basicity for targeted drug design.

Application

2-Amino-5-fluoropyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to fluorinated heterocyclic scaffolds. Its dual functionalization—amine and fluorine—supports diverse transformations including Suzuki-Miyaura coupling, nucleophilic substitution, and transition-metal-catalyzed cross-couplings. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthetic campaigns and API intermediate development.

General Information

CAS No. 21717-96-4
Cat. No. CS-B0957
Purity ≥98%
MDL No. MFCD01861120
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₅FN₂
Molecular Weight 112.11
Synonym(s) None
SMILES NC1=NC=C(F)C=C1

Computational Chemistry Data

TPSA 38.91
LogP 0.8029
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2-Amino-5-fluoropyridine

CAS No. 21717-96-4

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