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(R)-3-(Methoxymethyl)morpholine hydrochloride

  • CAS No. 218594-74-2

  • Cat. No. CS-0061891
  • Purity≥97%
  • MDL No.MFCD09608106

*For research and further manufacturing use only, not for direct human use.

(R)-3-(Methoxymethyl)morpholine hydrochloride|CS-0061891

Structure of 218594-74-2

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General Information

  • CAS No. 218594-74-2
  • Cat. No. CS-0061891
  • Purity ≥97%
  • MDL No. MFCD09608106
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₄ClNO₂
  • Molecular Weight 167.63
  • Synonym(s) (R)-3-Methoxymethyl-morpholine hydrochloride
  • SMILES COC[C@@H]1COCCN1.Cl

Description

(R)-3-(Methoxymethyl)morpholine hydrochloride offers a bench-stable, moisture-tolerant chiral scaffold with enhanced solubility in aqueous and polar organic media. This configuration enables efficient incorporation into asymmetric synthesis workflows, particularly in the development of bioactive heterocycles and pharmaceutical intermediates.

Application

(R)-3-(Methoxymethyl)morpholine hydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling the synthesis of morpholine-containing scaffolds with defined stereochemistry. Its bench-stable hydrochloride salt form facilitates handling and purification, while the methoxymethyl group offers orthogonal protection for amine functionalization. The compound reacts predictably in standard coupling and cyclization protocols, supporting efficient access to complex heterocyclic intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   30.49
  • LogP   0.043
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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