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Structure of 220141-73-1
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3',4',5'-Trifluoroacetophenone features a trifluoromethyl-substituted aromatic ring paired with a reactive ketone group, enabling direct incorporation into cross-coupling and electrophilic functionalization sequences. The electron-deficient aryl system enhances reactivity in transition metal-catalyzed transformations, while the bench-stable ketone facilitates reliable handling under standard conditions.
3',4',5'-Trifluoroacetophenone serves as a valuable building block in medicinal chemistry and agrochemical synthesis, offering enhanced metabolic stability and modulated lipophilicity due to its trifluoromethyl-substituted aromatic ring. The ketone functionality enables straightforward transformations including nucleophilic additions, reductions, and condensation reactions, facilitating access to complex heterocyclic scaffolds. Its bench-stable nature and compatibility with common synthetic protocols make it a practical choice for multi-step sequences.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: