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Structure of 220497-47-2
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Fmoc-Phe(2-Br)-OH is a sterically hindered, electron-deficient phenylalanine derivative featuring a bromine substituent at the ortho position. This modification enhances its utility in peptide synthesis by improving coupling efficiency and reducing side reactions. The Fmoc group enables efficient, orthogonal protection for N-terminal amine handling under standard conditions.
Fmoc-Phe(2-Br)-OH serves as a valuable building block in peptide synthesis, enabling the incorporation of ortho-bromophenylalanine into peptide sequences. The bromine substituent provides a handle for subsequent palladium-catalyzed cross-coupling reactions, facilitating late-stage diversification. Its Fmoc protection ensures compatibility with standard solid-phase synthesis protocols, while the side chain's stability and ease of purification support efficient workflow integration.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: