6-Chloro-1H-indazol-5-amine

Name: 6-Chloro-1H-indazol-5-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 221681-75-0
Cat. No. CS-0130401
Purity≥98%
MDL No.MFCD08690108

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 221681-75-0

Size

Price

Quantity

* Please select Quantity before adding items.

Description

6-Chloro-1H-indazol-5-amine is a bench-stable heterocyclic amine featuring a chlorine substituent at the 6-position and a primary amine at the 5-position. This electron-deficient scaffold integrates readily into pharmaceutical intermediates, enabling efficient coupling reactions in medicinal chemistry. The para-chloro functionality enhances reactivity in cross-coupling processes, while the indazolyl core provides structural rigidity for targeted bioactive molecule design.

Application

6-Chloro-1H-indazol-5-amine serves as a versatile building block for medicinal chemistry and heterocyclic synthesis, enabling efficient construction of indazole-based scaffolds. Its chlorine substituent facilitates palladium-catalyzed cross-coupling reactions, while the primary amine allows for direct derivatization via acylation, alkylation, or Ullmann-type coupling. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for high-throughput screening and API development workflows.

General Information

CAS No. 221681-75-0
Cat. No. CS-0130401
Purity ≥98%
MDL No. MFCD08690108
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆ClN₃
Molecular Weight 167.60
Synonym(s) 5-AMINO-6-CHLORO (1H)INDAZOLE
SMILES NC1=CC2=C(NN=C2)C=C1Cl

Computational Chemistry Data

TPSA 54.7
LogP 1.7985
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Indazole compounds

Key Words

6-Chloro-1H-indazol-5-amine sigma6-Chloro-1H-indazol-5-amine manufacturer6-Chloro-1H-indazol-5-amine price6-Chloro-1H-indazol-5-amine structure6-Chloro-1H-indazol-5-amine SDSbuy 6-Chloro-1H-indazol-5-amine6-Chloro-1H-indazol-5-amine supplier6-Chloro-1H-indazol-5-amine uses6-Chloro-1H-indazol-5-amine molecular weightprice of 6-Chloro-1H-indazol-5-amine6-Chloro-1H-indazol-5-amine chemical name formula of 6-Chloro-1H-indazol-5-amine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Chloro-1H-indazol-5-amine

CAS No. 221681-75-0

Recommended Products