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Structure of 22282-70-8
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2-Fluoro-4-iodopyridine is a halogenated pyridine derivative featuring orthogonal reactivity between fluorine and iodine. This dual-functional motif enables selective cross-coupling transformations in late-stage diversification. The electron-deficient ring enhances compatibility with palladium catalysis, while the bench-stable nature simplifies handling in synthetic workflows.
2-Fluoro-4-iodopyridine serves as a versatile building block in cross-coupling chemistry, enabling efficient Suzuki, Stille, and Negishi reactions due to its orthogonal reactivity profile. The fluorine and iodine substituents offer complementary functionalization potential, facilitating sequential transformations. Bench-stable and readily purified, it functions effectively in the synthesis of biologically active heterocycles and pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: