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Structure of 222978-02-1
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2-Fluoro-4-(hydroxymethyl)benzonitrile features a strategically positioned nitrile group and fluorinated aromatic ring, enabling integration into bioactive scaffolds. The hydroxymethyl functionality offers a handle for derivatization, while the electron-withdrawing nitrile enhances metabolic stability. This compound serves as a key building block in medicinal chemistry for targeted molecular design.
2-Fluoro-4-(hydroxymethyl)benzonitrile serves as a versatile building block for medicinal chemistry and heterocyclic synthesis. The nitrile group enables efficient transformations to amides, carboxylic acids, or amidines, while the hydroxymethyl moiety supports oxidation, protection, or coupling reactions. Fluorine substitution enhances metabolic stability and modulates electronic properties. This compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for scalable synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: