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CS-W001157 4
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Tert-butyl 4-(pyridin-3-yl)piperazine-1-carboxylate

  • CAS No. 223797-47-5

  • Cat. No. CS-0449897
  • Molecule weight263.34
  • Purity≥98%
  • MDL No.MFCD11872568

*For research and further manufacturing use only, not for direct human use.

Tert-butyl 4-(pyridin-3-yl)piperazine-1-carboxylate|CS-0449897

Structure of 223797-47-5

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General Information

  • CAS No. 223797-47-5
  • Cat. No. CS-0449897
  • Purity ≥98%
  • MDL No. MFCD11872568
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₁N₃O₂
  • Molecular Weight 263.34
  • Synonym(s) 1-(3-pyridyl)-4-tert-butoxycarbonylpiperazine
  • SMILES CC(C)(C)OC(=O)N1CCN(CC1)C2=CN=CC=C2

Synthesis

  • Route1
    • In-stock
      3-Bromopyridine|CS-0008362
      626-55-1
    • N-Boc-piperazine Olaparib Impurity|CS-0214004
      57260-71-6
    • ~61%
    • In-stock
      Tert-butyl 4-(pyridin-3-yl)piperazine-1-carboxylate|CS-0449897
      223797-47-5

    References

    • AMGEN INC. Patent: WO2009/85185 A1, 2009 ; Location in patent: Page/Page column 114-115 ; WO 2009/085185 A1
  • Route2

    References

    • Audouze, Karine; Nielsen, Elsebet stergaard; Olsen, Gunnar M.; Ahring, Philip; Jorgensen, Tino Dyhring; Peters, Dan; Liljefors, Tommy; Balle, Thomas Journal of Medicinal Chemistry, 2006 , vol. 49, # 11 p. 3159 - 3171

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   45.67
  • LogP   2.1387
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

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