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CS-W001157 4
Total: USD 88.00

Potassium trifluoro(2-(trifluoromethyl)benzyl)borate

  • CAS No. 2248620-18-8

  • Cat. No. CS-0567219
  • Molecule weight266.03
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Potassium trifluoro(2-(trifluoromethyl)benzyl)borate|CS-0567219

Structure of 2248620-18-8

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General Information

  • CAS No. 2248620-18-8
  • Cat. No. CS-0567219
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆BF₆K
  • Molecular Weight 266.03
  • Synonym(s) None
  • SMILES FC(C1=CC=CC=C1C[B-](F)(F)F)(F)F.[K+]

Description

Potassium trifluoro(2-(trifluoromethyl)benzyl)borate delivers a sterically accessible boronate handle with enhanced stability and solubility in polar solvents. This bench-stable reagent enables direct C–H functionalization and Suzuki–Miyaura coupling under mild conditions, leveraging the electron-deficient aryl framework for efficient cross-coupling with diverse partners.

Application

Potassium trifluoro(2-(trifluoromethyl)benzyl)borate serves as a stable, bench-friendly boron reagent enabling efficient Suzuki-Miyaura cross-coupling reactions. Its trifluoromethyl-substituted benzyl group confers enhanced functional group tolerance and improved oxidative stability, facilitating reliable C–C bond formation under standard catalytic conditions. This reagent functions effectively in the construction of biaryl scaffolds and complex heterocycles relevant to pharmaceutical synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   0.6385
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   2

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