(2-Phenylthiazol-4-yl)methanol

Name: (2-Phenylthiazol-4-yl)methanol
Brand: ChemScene
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CAS No. 23780-13-4
Cat. No. CS-0094481
Purity≥98%
MDL No.MFCD02682017

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FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(2-Phenylthiazol-4-yl)methanol|CS-0094481

Structure of 23780-13-4

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Description

This bench-stable, moisture-tolerant building block features a phenylthiazole core with a reactive alcohol handle. The para-positioned phenyl group enhances electron delocalization, while the aldehyde functionality enables direct coupling or oxidation to carboxylic acid derivatives in synthetic workflows.

Application

(2-Phenylthiazol-4-yl)methanol serves as a versatile building block in medicinal chemistry, enabling efficient access to thiazole-based scaffolds. Its benzyl-like functionality facilitates electrophilic coupling and oxidation to carboxylic acid derivatives. The molecule exhibits bench stability, tolerates common functional groups, and functions effectively in standard cross-coupling and derivatization protocols.

General Information

CAS No. 23780-13-4
Cat. No. CS-0094481
Purity ≥98%
MDL No. MFCD02682017
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₉NOS
Molecular Weight 191.25
Synonym(s) 4-(HYDROXYMETHYL)-2-PHENYLTHIAZOLE
SMILES OCC1=CSC(C2=CC=CC=C2)=N1

Computational Chemistry Data

TPSA 33.12
LogP 2.3024
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 2

Safety Information

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GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Thiazole compounds

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

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(2-Phenylthiazol-4-yl)methanol

CAS No. 23780-13-4

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