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Structure of 240401-27-8
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tert-Butyl 2-oxa-7-azaspiro[3.5]nonane-7-carboxylate is a sterically shielded spirocyclic heterocycle featuring a stable oxazepine core and a bench-stable tert-butyl ester. This scaffold integrates a nitrogen atom at the spiro junction and an oxygen bridge, enabling precise control over conformational rigidity and solubility. The protected carboxylate group facilitates downstream derivatization in synthetic sequences involving macrocyclization or medicinal chemistry optimization.
tert-Butyl 2-oxa-7-azaspiro[3.5]nonane-7-carboxylate serves as a versatile spirocyclic scaffold for medicinal chemistry, enabling the construction of constrained heterocycles with defined stereochemistry. The protected amine and ester functionalities offer orthogonal reactivity, facilitating downstream transformations such as hydrogenolysis, hydrolysis, or coupling reactions. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for iterative synthesis and library generation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: