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Structure of 2459401-08-0
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Methyl 3,3-difluoro-2-oxocyclopentane-1-carboxylate features a strained cyclopentanone ring bearing two fluorine atoms at the geminal 3-position and a methyl ester group. This electron-deficient scaffold integrates readily into asymmetric synthesis workflows, offering enhanced reactivity in nucleophilic additions and enabling access to fluorinated carbocyclic building blocks under mild conditions.
Methyl 3,3-difluoro-2-oxocyclopentane-1-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling the construction of fluorinated cyclopentane scaffolds relevant to medicinal chemistry. The gem-difluoro substituent imparts enhanced metabolic stability and modulates electronic properties, while the α,β-unsaturated carbonyl system facilitates nucleophilic addition and Michael-type reactions. Its bench-stable nature and compatibility with standard functional group manipulations make it well-suited for iterative synthesis and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: