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Structure of 24630-67-9
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Dimethyl (hydroxymethyl)phosphonate features a phosphonate group tethered to a hydroxymethyl moiety, enabling direct incorporation into phosphorylated intermediates. This bench-stable reagent delivers a reactive handle for synthetic transformations in medicinal chemistry and materials science.
Dimethyl (hydroxymethyl)phosphonate serves as a versatile building block in phosphorus chemistry, enabling efficient access to α-hydroxyphosphonates through nucleophilic addition and subsequent functionalization. Its hydroxymethyl group offers a handle for further derivatization, while the phosphonate moiety facilitates C–C bond formation via Horner-Wadsworth-Emmons or related olefination reactions. The compound exhibits good bench stability and compatibility with standard reaction conditions, simplifying purification and integration into synthetic sequences for medicinal chemistry and materials applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: