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Structure of 248274-04-6
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This boronate-functionalized arylmethylamine integrates seamlessly into cross-coupling workflows, offering enhanced stability and solubility under standard conditions. The tetramethylcyclopentadienone-derived boronate moiety enables efficient Suzuki-Miyaura coupling, while the primary amine group facilitates downstream derivatization. Bench-stable and moisture-tolerant, this reagent streamlines access to complex biaryl architectures in synthetic and medicinal chemistry applications.
[2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methanamine serves as a versatile boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The pendant amine group enables direct functionalization or incorporation into bioactive scaffolds, while the stable dioxaborolane moiety facilitates mild reaction conditions and excellent functional group tolerance. Ideal for late-stage diversification in medicinal chemistry and materials synthesis.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: