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CS-W001157 4
Total: USD 88.00

4-(Oxazol-5-yl)benzoic acid

  • CAS No. 250161-45-6

  • Cat. No. CS-0083897
  • Purity≥98%
  • MDL No.MFCD02682033

*For research and further manufacturing use only, not for direct human use.

4-(Oxazol-5-yl)benzoic acid|CS-0083897

Structure of 250161-45-6

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General Information

  • CAS No. 250161-45-6
  • Cat. No. CS-0083897
  • Purity ≥98%
  • MDL No. MFCD02682033
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇NO₃
  • Molecular Weight 189.17
  • Synonym(s) 4-(1,3-Oxazol-5-yl)benzoic Acid
  • SMILES O=C(O)C1=CC=C(C2=CN=CO2)C=C1

Description

4-(Oxazol-5-yl)benzoic acid integrates a polar oxazolyl heterocycle with an aromatic carboxylic acid, enabling robust conjugation in medicinal chemistry. This scaffold delivers enhanced solubility and metabolic stability while maintaining favorable binding interactions in target-directed synthesis.

Application

4-(Oxazol-5-yl)benzoic acid serves as a versatile building block for heterocyclic scaffolds and bioactive molecule synthesis. Its conjugated aryl-oxazole architecture enables efficient coupling reactions, including amide formation and Suzuki-Miyaura cross-coupling, with excellent bench stability and straightforward purification. The carboxylic acid group provides direct access to esters, amides, and other derivatives, facilitating integration into pharmaceutical and agrochemical discovery pipelines.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.33
  • LogP   2.0398
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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