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CS-W001157 4
Total: USD 88.00

DMT-2'O-MOE-rG(ib) Phosphoramidite

  • CAS No. 251647-55-9

  • Cat. No. CS-0023712
  • Purity≥95%
  • MDL No.MFCD00792625

*For research and further manufacturing use only, not for direct human use.

DMT-2'O-MOE-rG(ib) Phosphoramidite|CS-0023712

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General Information

  • CAS No. 251647-55-9
  • Cat. No. CS-0023712
  • Purity ≥95%
  • MDL No. MFCD00792625
  • Storage -20°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₇H₆₀N₇O₁₀P
  • Molecular Weight 913.99
  • Synonym(s) None
  • SMILES COCCO[C@@H]1[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)O[C@H]1N5C=NC6=C5N=C(NC6=O)NC(C(C)C)=O

Description

DMT-2'O-MOE-rG(ib) phosphoramidite enables rapid incorporation of sterically hindered, hydrolysis-resistant 2'-O-methoxyethyl-modified guanosine into oligonucleotides. This derivative delivers enhanced nuclease stability and improved binding affinity in antisense applications, streamlining synthesis of next-generation therapeutic nucleic acids under standard conditions.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P301+P310-P330-P501

Quality Control

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Computational Chemistry Data

  • TPSA   193.54
  • LogP   7.33018
  • H_Acceptors   15
  • H_Donors   2
  • Rotatable_Bonds   23

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