Thiophen-3-amine hydrochloride

Name: Thiophen-3-amine hydrochloride
Brand: ChemScene
Availability: InStock
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CAS No. 25475-76-7
Cat. No. CS-D0258
Purity≥95%
MDL No.MFCD11226843

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Description

Thiophen-3-amine hydrochloride offers a readily accessible, bench-stable source of the thiophene-3-amine scaffold. This water-soluble salt facilitates efficient incorporation into synthetic sequences requiring nitrogen functionality at the 3-position of thiophene. The protonated amine enhances solubility and handling in aqueous or polar media, streamlining use in medicinal chemistry and materials synthesis workflows.

Application

Thiophen-3-amine hydrochloride serves as a versatile building block in synthetic organic chemistry, enabling direct incorporation of the thiophene scaffold into pharmaceutical and agrochemical intermediates. Its amine functionality facilitates straightforward derivatization via amidation, alkylation, and electrophilic substitution reactions. The hydrochloride salt enhances bench stability and simplifies handling and purification, making it well-suited for scalable synthesis and routine laboratory workflows.

General Information

CAS No. 25475-76-7
Cat. No. CS-D0258
Purity ≥95%
MDL No. MFCD11226843
Storage 4°C, protect from light, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₄H₆ClNS
Molecular Weight None
Synonym(s) 3-aminothiophene hydrochloride
SMILES NC1=CSC=C1.Cl

Computational Chemistry Data

TPSA 26.02
LogP 1.7521
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Thiophene compounds

Key Words

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Thiophen-3-amine hydrochloride

CAS No. 25475-76-7

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