2,6-Dichloro-4-pyridinamine

Name: 2,6-Dichloro-4-pyridinamine
Brand: ChemScene
Availability: InStock
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CAS No. 2587-02-2
Cat. No. CS-W008199
Purity≥98%
MDL No.MFCD00052832

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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Structure of 2587-02-2

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Description

2,6-Dichloro-4-pyridinamine serves as a key heterocyclic building block for pharmaceutical intermediates and agrochemical synthesis. The molecule features two electron-withdrawing chlorine substituents at the 2- and 6-positions, enhancing electrophilicity at the 4-position where the amino group is anchored. This configuration enables efficient coupling reactions under mild conditions. The compound exhibits bench-stable handling characteristics and compatibility with diverse reaction systems.

Application

2,6-Dichloro-4-pyridinamine serves as a versatile building block for heterocyclic synthesis, enabling efficient access to substituted pyridine scaffolds via palladium-catalyzed cross-coupling reactions. Its dual chlorine substituents provide orthogonal reactivity for sequential functionalization, while the primary amine facilitates derivatization and conjugation. Bench-stable and readily purified, it functions effectively in medicinal chemistry and agrochemical research workflows.

General Information

CAS No. 2587-02-2
Cat. No. CS-W008199
Purity ≥98%
MDL No. MFCD00052832
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₄Cl₂N₂
Molecular Weight 163.01
Synonym(s) None
SMILES ClC1=CC(N)=CC(Cl)=N1

Computational Chemistry Data

TPSA 38.91
LogP 1.9706
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Dye and Bio-assay Reagents

Building Blocks Functional Group Amine

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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2,6-Dichloro-4-pyridinamine

CAS No. 2587-02-2

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