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Structure of 25900-61-2
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3-Amino-N-methylbenzamide features a strategically positioned amino group and methylated amide, enhancing solubility and metabolic stability. This combination enables direct incorporation into peptide scaffolds and bioactive molecules, offering improved membrane permeability and resistance to enzymatic degradation in medicinal chemistry applications.
3-Amino-N-methylbenzamide serves as a versatile building block in medicinal chemistry, enabling direct access to substituted benzamide scaffolds through standard amide coupling and electrophilic substitution reactions. Its amino group facilitates derivatization via acylation, alkylation, or diazotization, while the N-methylated amide offers enhanced metabolic stability and favorable logP profiles. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses of kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅱ
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: